张世卿博士，副研究员，硕士生导师 

个人简介：

张世卿，博士，副研究员。2016年毕业于香港浸会大学，获博士学位，同年在香港浸会大学理学院进行博士后研究，2019年获聘为香港浸会大学理学院研究助理教授，2021年进入暨南大学药学院工作。主要研究神经退行性疾病病理机制及药物干预策略，善于利用中药及天然药物有效成分治疗神经退行性疾病。以第一作者/通讯作者在Advanced Science、Acta Pharmacologica Sinica、Journal of Ginseng Research、Phytomedicine及Frontiers in Pharmacology等期刊发表论文多篇。主持国家自然科学基金青年科学基金项目1项及广东省自然科学基金面上项目1项。荣获日本癌症协会青年科学家奖，代表香港参加第70届林道诺贝尔奖得主大会。

教育经历:

09/2013 - 09/2016      博士，神经生物学，香港浸会大学

09/2009 - 06/2012      硕士，中药药理学，南方医科大学

09/2005 - 06/2009      学士，中药学，南方医科大学

科研与学术工作经历:

10/2019 - 07/2021      研究助理教授，理学院，香港浸会大学

10/2016 - 10/2019      博士后，理学院，香港浸会大学

代表论文：  

1. Jiang XL^#, Deng B^#, Deng SH^#, Cai M, Tian ZB, Chen RX, Xu YC, Ding WJ, Xu HL, Zhang SW, Zhang SQ*, Liu B*, Zhang JZ*. Dihydrotanshinone I inhibits the growth of hepatoma cells by direct inhibition of Src. Phytomedicine. 2022, 95: 153705.

2. Wu XY^#, Lv JY^#, Zhang SQ^#, Yi X, Xu ZW, Zhi YX, Zhao BX, Pang JX, Yung K*, Liu SW*, Zhou PZ*. ML365 inhibits TWIK2 channel to block ATP-induced NLRP3 inflammasome. Acta pharmacologica Sinica. 2021, 10.1038/s41401-021-00739-9.

3. Zhang SQ^#, Jiang XL^#, Wang Y, Lin KL, Zhang Z, Zhang Z, Ng ML, Qu SG, Sze SCW*, Yung KKL*. Protective Effect of An-Gong-Niu-Huang Wan Pre-treatment against Experimental Cerebral Ischemia Injury via Regulating GSK-3β/HO-1 Pathway. Frontiers in Pharmacology. 2021, 16: 640297.

4. Lin KL^#, Sze SCW^#, Liu B, Zhang Z, Zhang Z, Zhu PL, Wong Y, Deng QD, Yung KKL*, Zhang SQ*. 20(S)-protopanaxadiol and oleanolic acid ameliorate cognitive deficits in APP/PS1 transgenic mice by enhancing hippocampal neurogenesis. Journal of Ginseng Research. 2021, 45: 325-333.

5. Zhang SQ^#, Sun P^#, Lin K^#, Chan FHL, Gao Q, Lau WF, Roy VAL, Zhang HQ, Lai KWC*, Huang ZF*, Yung KKL*. Extracellular nanomatrix-induced self-organization of neural stem cells into miniature substantia nigra-like structures with therapeutic effects on Parkinsonian rats. Advanced Science. 2019, 6(24): 1901822.

6. Lin KL^#, Liu B^#, Lim SL, Fu XQ, Sze SCW, Yung KKL*, Zhang SQ*. 20(S)-protopanaxadiol promotes the migration, proliferation and differentiation of neural stem cells by targeting GSK-3β in the Wnt/GSK-3β/β-catenin pathway. Journal of Ginseng Research. 2020, 44: 475-482.

7. Zhang Z^#, Zhang SQ^#, Lui CNP, Zhu PL, Zhang Z, Lin KL, Dai YW*, Yung KKL*. Traditional Chinese medicine-based neurorestorative therapy for Alzheimer’s and Parkinson’s disease. Journal of Neurorestoratology. 2019, 07: 207-222.

8. Zhang Zhu^#, Zhang SQ^#, Fu PF, Zhang Z, Lin KL, Ko JKS*, Yung KKL*. Roles of Glutamate Receptors in Parkinson’s Disease. Int. J. Mol. Sci. 2019, 20(18): 4391.

9. Lv JY^#, Liang YM^#, Zhang SQ^#, Lan QS, Xu ZW, Wu XY, Kang LJ, Ren J, Cao Y, Wu T, Lin KL, Yung KKL, Cao X*, Pang JX*, Zhou PZ*. DCPIB, an inhibitor of volume-regulated anion channels, distinctly modulates K2P channels. ACS Chemical Neuroscience.2019, 10: 2786-2793.

10. Zhang SQ^#, Yung KK^#, Chung SK, Chung SS*. Aldo-keto reductases mediated cytotoxicity of 2-deoxy-d-glucose: a novel anticancer mechanism. Cancer Science. 2018, 109(6): 1970-1980.

代表性科研项目

1. 国家自然科学基金青年科学基金项目（项目编号：81703728；主持）

2. 广东省自然科学基金面上项目（项目编号：2019A1515011497；主持）

邮箱：

sqzhang@jnu.edu.cn