Pubmed文章列表 | Google Scholar文章列表 | Researchgate文章列表
2026年
Miaoqi Huang, Han Ye, Yong Xu, Jiaoyan Xie, Xinyu Wang, Yan Luo, Peng Liu, Xuanyue Ma, Shiqing Zhang, Bin Jiang, Wen-Cai Ye*, Yinghui Peng*, Lei Shi*.
Correction of eIF4E overactivation rescues translatome imbalance and core ASD-like behaviors in valproic acid-induced offspring mice.
Molecular Psychiatry, 2026, doi: 10.1038/s41380-026-03517-3. Online ahead of print.
PMID: 41795048; Journal Website
相关报道：药学院师蕾/叶文才教授团队揭示孤独症“蛋白质合成稳态失衡”共性机制及靶向策略
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2025年
Daji Guo, Mengjiao Cai, Yanmin Xian, Yinyin Chen, Yujun Feng, Chun Hu, Lizhang Zeng*, Lei Shi*, Shiqing Zhang*.
Transient Receptor Potential Channels as Key Regulators of Neuroinflammation in Neurological Disorders: Mechanistic Insights, Therapeutic Potentials, and Future Directions.
CNS Neurosci Ther. 2025, 31(12):e70700.
PMID: 41399206 https://pubmed.ncbi.nlm.nih.gov/41399206/
Journal Website: https://onlinelibrary.wiley.com/doi/full/10.1002/cns.70700
Yuanyuan Song, Shiqing Zhang, Siru Yang, Xiaoke Gao, Lei Shi, Jinjian Chen, Kaili Lin*, Jun Yang*.
Long-Term Urban Air Pollution Drives Multi-Stage Neuropsychiatric Disorder Trajectories: A Prospective Cohort Study.
Toxics. 2025;14(1):4.
PMID: 41600553 https://pubmed.ncbi.nlm.nih.gov/41600553/
Journal Website: https://pmc.ncbi.nlm.nih.gov/articles/PMC12845905/
Su X, Zang J, Wang Y, Zhang S, Wu P, Chen W, Shi L, Wu Y, Deng D, Cai K, Mai H, Xu A, Lu D*.
IGF2BP1 positively regulates CircOGDH accumulation in hypoxia induced stress granules. Acta Pharm Sin B. 2025, 15(12):6478-6494.
PMID: 41477335; https://pubmed.ncbi.nlm.nih.gov/41477335/
Journal Website: https://pmc.ncbi.nlm.nih.gov/articles/PMC12750160/
Yan C, Yan SR, Zhu Y, Cai M, Huang RL, Wang X, Zhang S, Shi L, Hu LJ, Ye WC, Huang XJ, Wang Y, Song JG*.
Eugenol-based meroterpenoids with neural differentiation activity from Eugenia caryophyllata.
Phytochemistry. 2025, 239:114588.
PMID: 40533035; https://pubmed.ncbi.nlm.nih.gov/40533035/
Journal Website: https://www.sciencedirect.com/science/article/pii/S0031942225002110?via%3Dihub
Kawashita E*, Fukuzaki Y, Fischer J, Shi L, Liao Y, Millar LJ, Zhong P, Hoerder-Suabedissen A, Soares LC*, Molnár Z*.
Neuroserpin: A Potential Neuroprotective Agent in Mild Neonatal Hypoxic-Ischaemic Encephalopathy.
Cells. 2025, 21;14(23):1840.
PMID: 41369329; https://pubmed.ncbi.nlm.nih.gov/41369329/
Journal Website: https://pmc.ncbi.nlm.nih.gov/articles/PMC12691123/
Pan N, Li KY, Huang SJ, Lin LZ, Shi L, Feng Q, Chen Y, Ren AQ, Cai L, Weng XC, Wang X*.
Breastfeeding initiation and duration: links to physical, mental and behavioural health in US children aged 3-5 years.
BMJ Nutr Prev Health. 2025, 8(2):e001175.
PMID: 41502573; https://pubmed.ncbi.nlm.nih.gov/41502573/
Journal Website: https://pmc.ncbi.nlm.nih.gov/articles/PMC12772619/
Niping Li, Yaorong Yang, Shengyuan Zhang, Bin Jiang, Wei Zhang, Haibo Wang, Lixin Chen, Liwei Wang, Yiyi Li, Lei Shi*, Wencai Ye*, Lei Wang*.
The toxic components, toxicological mechanism and effective antidote for Gelsemium elegans poisoning.
Acta Pharmaceutica Sinica B, 2025, 15(9), 4872-4885.
PMID: 41049747 https://pubmed.ncbi.nlm.nih.gov/41049747/
Journal Website: https://www.sciencedirect.com/science/article/pii/S2211383525004915
Lijiao Zu, Xicheng Wang, Peng Liu, Jiwei Xie, Claudia Borri, Rukmani Singh, Shadab Dabagh, Ambra Giannetti, Xuejun Zhang, Weiru Liu, Zhencheng Li, Shiqing Zhang, Kaiwei Li, Wei Bi, Francesco Chiavaioli, Lei Shi, Tuan Guo*.
Unveiling simultaneous detection and identification of different forms of amyloid-β peptides in Alzheimer’s disease via multi-channel TFBG-SPR biosensor.
Conference: 29th International Conference on Optical Fiber Sensors
DOI:10.1117/12.3060991; May 2025
Ren T, Miao Q, Pan Y, Zhang S, Shi L, Wang Y, Ye WC, Wu ZL, Huang XJ, Song JG*. Diarylheptanoid-flavanone adducts from Alpinia officinarum and their neuroprotective activities.
Fitoterapia. 2025, 184:106594.
PMID: 40339616; https://pubmed.ncbi.nlm.nih.gov/40339616/
Journal Website: https://www.sciencedirect.com/science/article/pii/S0367326X25002199?via%3Dihub
Xie Q, Pan N, Ou X, Shen S, Jing J, Weng X, Shi L, Lin L, Yang J, Li X, Zhang K, Chen F, Wang Y, Wu J, Wang X*.
Chronic Physical Pain in Children With and Without Autism Spectrum Disorder in the United States: Findings from the 2016 - 2021 National Survey of Children's Health.
J Autism Dev Disord. 2025, doi: 10.1007/s10803-025-06846-4. Epub ahead of print.
PMID: 40301196; http://pubmed.ncbi.nlm.nih.gov/40301196/
Journal Website: https://link.springer.com/article/10.1007/s10803-025-06846-4#citeas
Wang Shu-Qin#, Wang Xinyu#, Guo Lingling, Chen Xiao-Xia, Huang Xiao-Jun, Zhang Shiqing, Ye Wen-Cai, Zhang Xiao-Qi, Shi Lei*, Wang Ying*, Hu Li-Jun*.
In-Silico Screening-Based Discovery of New Natural eEF2K Inhibitors with Neuritogenic Activity.
ACS Medicinal Chemistry Letters, 2025, 16(3), 475–482.
PMID: 40104800; Journal Website
Liao Yumei#, Che Dongyang#, Liu Peng#, Wang Xinyu#, Zhang Yanlin, Guo Lingling, Hu Jinlin, Li Tianyao, Lam Mei Fong, Ma Nan*, Zhang Shiqing*, Lu Hua*, Shi Lei*, Zhang Xiaoshen*.
Deep Hypothermic Low Flow Results in Multiple Aspects of Neurological Deficits in Mice by eEF2 Hyperphosphorylation.
Molecular Neurobiology, 2025 Feb, doi: 10.1007/s12035-025-04784-x. Online ahead of print.
PMID: 40014267; Journal Website
Wang Chaoqun#, Lin Kaili#, Zhang Zhu#, Pan Yan, Miao Qiuping, Han Xiaohe, Zhang Zhang, Zhu Peili, Yang Jun, Peng Yinghui, Yung Ken Kin-Lam*, Shi Lei*, Zhang Shiqing*.
Adolescent exposure to micro/nanoplastics induces cognitive impairments in mice with neuronal morphological damage and multi-omic alterations.
Environment International, 2025, 197, 109323.
PMID: 39954360; Journal Website
Wang Xin, Shen Le-Le, Pan Shuo-Lin, Jing Jin, Shi Lei, Weng Xu-Chu, Li Xiu-Hong, Lin Li-Zi*, Pan Ning*.
A latent profile analysis of empathizing-systemizing cognitive style among Chinese children aged 6 - 12 years: Links to intelligence, executive function, and autistic traits.
International Journal of Clinical and Health Psychology, 2025, 25(1), 100554.
PMID: 40035036; Journal Website
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2024年
Jiang Yan#, Guo Cuihua#, Kuang Min#, Lin Lizi, Xu Guifeng, Pan Ning, Weng Xuchu, Jing Jin, Shi Lei, Yi Quanying*, Wang Xin*.
Examining associations of folic acid supplements administered to mothers during pre-conceptional and prenatal periods with autism spectrum disorders in their offspring: insights from a multi-center study in China.
Frontiers in Public Health. 2024 Jan 17:12:1321046.
PMID: 38299071；Journal Website
Zu Lijiao#, Wang Xicheng#, Liu Peng#, Xie Jiwei#, Zhang Xuejun, Liu Weiru, Li Zhencheng, Zhang Shiqing, Li Kaiwei, Giannetti Ambra, Bi Wei*, Chiavaioli Francesco*, Shi Lei*, Guo Tuan*.
Ultrasensitive and Multiple Biomarker Discrimination for Alzheimer’s Disease via Plasmonic & Microfluidic Sensing Technologies.
Advanced Science, 2024 March, 11(24), 2470138.
Liao Yumei#, Zhang Qinghua#, Shi Qiaoyun#, Liu Peng, Zhong Peiyun, Guo Lingling, Huang Zijian, Peng Yinghui, Liu Wei, Zhang Shiqing, Adorján István, Fukuzaki Yumi, Kawashita Eri, Zhang Xiao-Qi, Ma Nan*, Zhang Xiaoshen*, Molnár Zoltán*, Shi Lei*.
Neuroserpin alleviates cerebral ischemia-reperfusion injury by suppressing ischemia-induced endoplasmic reticulum stress.
Neural Regeneration Research, 2024 September, 21(1):2017-2021.
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2023年
Yuxin Gao#, Yuan Guo, Yaorong Yang, Yanping Tang, Biao Wang, Qihang Yan, Xiyu Chen,Junxiang Cai, Li Fang, Ze Xiong, Fei Gao, Changjin Wu, Jizhuang Wang,* Jinyao Tang, Lei Shi*, Dan Li*.
Magnetically Manipulated Optoelectronic Hybrid Microrobots for Optically Targeted Non‐Genetic Neuromodulation.
(2023) Advanced Materials. 2023 Oct 8; e2305632.
PMID: 37805826; Journal Website
相关报道：化学与材料学院王吉壮/李丹教授团队与药学院师蕾教授团队在Adv. Mater.发表重要研究成果
暨南大学王吉壮/李丹教授团队与师蕾教授团队Adv. Mater.：硅基复合微机器人用于精准光神经调节
Xiao-Ling Zhan#, Ning Pan#, Shamshad Karatela, Lei Shi, Xin Wang, Zhao-Yan Liu, Jin Jing, Xiu-Hong Li, Li Cai, Li-Zi Lin*.
Infant feeding practices and autism spectrum disorder in US children aged 2-5 years: the national survey of children's health (NSCH) 2016-2020.
(2023) International Breastfeeding Journal. 2023 Aug 11;18(1):41.
PMID: 37568201; Journal Website
Ning Pan#, Li-Zi Lin, Xin Wang,Lei Shi, Xiao-Yu Xu, Yu-Ying Jin, Si Tan, Xiao-Jing Song, Jin Jing, Xiu-Hong Li*.
Brain structure underlying the empathizing-systemizing difference in children with autism spectrum disorder.
(2023) World Journal of Pediatrics. 2023 Aug;19(8):782-792.
PMID: 37273174; Journal Website
Zhi-Wen Liu, Min Song, Jun-Ya Wang, De-Zhi Wang, Biao Sun, Lei Shi, Ren-Wang Jiang, Min Ma, Xiao-Qi Zhang.
Monoterpenoid indole alkaloid adducts and dimers from Melodinus fusiformis.
(2023) Phytochemistry. 2023 Jul; 211:113678.
PMID: 37059289; Journal Website
Liao, Yumei#, Jun-Ya Wang, Yan Pan, Xueyi Zou, Chaoqun Wang, Yinghui Peng, Yun-Lin Ao, Mei Fong Lam, Xiaoshen Zhang, Xiao-Qi Zhang*, Lei Shi, Shiqing Zhang*.
The Protective Effect of (-)-Tetrahydroalstonine against OGD/R-Induced Neuronal Injury via Autophagy Regulation.
(2023) Molecules. 2023 Mar 4; 28(5):2370.
PMID: 36903613; Journal Website
Yinghui Peng#, Miaoqi Huang#, Jiaoyan Xie, Beiyi Shu, Xiaojun Wang, Yumei Liao, Junyu Xu, Lei Shi*.
Translational patterns of ionotropic glutamate and GABA receptors during brain development and behavioral stimuli revealed by polysome profiling.
(2023)Journal of Neurochemistry. 2023 Mar; 164(6):786-812.
PMID: 36695027; Journal Website
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2022年
Lijiao Zu#, Jiwei Xie, Peng Liu, Xuejun Zhang, Weiru Liu, Zhencheng Li, Shiqing Zhang, Lihong Zhu, Lei Shi, Tuan Guo, Kaiwei Li, Wei Bi, Francesco Chiavaioli*.
Ultra-sensitive Detection of Alzheimer’s Biosmarkers Using Plasmonic Optical Fiber Sensors.
(2022) Asia Communications and Photonics Conference, Shenzhen, China, 2022, pp. 2025-2028, doi: 10.1109/ACP55869.2022.10088486.
Cunzheng Li, Ji-An Wei, Diyang Wang, Zhihua Luo, Chaoqin Pang, Kai Chen, Juan Duan, Bailing Chen, Libing Zhou, Fadel Tissir, Lei Shi, Kwok-Fai So, Li Zhang*, Yibo Qu*.
Planar cell polarity protein Celsr2 maintains structural and functional integrity of adult cortical synapses.
(2022) Progress In Neurobiology. 2022 Dec. 219:102352
PMID: 36089108; Journal Website
Xuanyue Ma#, Liuren Li#, Ziming Li#, Zhengyi Huang, Yaorong Yang, Peng Liu, Daji Guo, Yueyao Li, Tianying Wu, Ruixiang Luo, Junyu Xu, Wen-Cai Ye*, Bin Jiang*, Lei Shi*.
eEF2 in the prefrontal cortex promotes excitatory synaptic transmission and social novelty behavior.
(2022) EMBO Reports. 2022 Aug 22. e54543
PMID: 35993189; Journal Website; PDF
Francesco Chiavaioli*, Desiree Santano Rivero, Ignacio Del Villar*, Abián B Socorro‐Leránoz, Xuejun Zhang, Kaiwei Li, Enrique Santamaría, Joaquín Fernández-Irigoyen, Francesco Baldini, Daniel LA van den Hove, Lei Shi, Wei Bi, Tuan Guo*, Ambra Giannetti, Ignacio R Matias.
Ultrahigh Sensitive Detection of Tau Protein as Alzheimer's Biomarker via Microfluidics and Nanofunctionalized Optical Fiber Sensors.
(2022) Advanced Photonics Research. 2022 July 18. DOI:10.1002/adpr.202200044
PMID; Journal Website; PDF
Daji Guo#,*, Xiaoman Yang#, Ming Gao#, Xiaoqing Chen, Yanping Tang, Lingling Shen, Keshen Li*, Lei Shi*.
Deficiency of autism-reulated gene Dock4 leads to impaired spatial memory and hippocampal function in mice at late middle age.
(2022) Cellular and Molecular Neurobiology. 2022 May 30. DOI:10.1007/s10571-022-01233-4
PMID: 35635601; Journal Website; PDF
Yanling Huang#, Yaorong Yang#, Yawen Zhao, Daji Guo, Linxi Chen, Lei Shi*, Geyang Xu*.
DOCK4 regulates ghrelin production in gastric X/A-like cells.
(2022) Journal of Endocrinological Investigation. 2022 Jul.45(7):1447-1454
PMID: 35302184; Journal Website; PDF
Rui Zheng#, Yonglan Du#, Xintai Wang, Tailin Liao, Zhe Zhang, Na Wang, Xiumao Li, Ying Shen, Lei Shi, Jianhong Luo*, Jun Xia*, Ziyi Wang*, Junyu Xu*.
KIF2C regulates synaptic plasticity and cognition in mice through dynamic microtubule depolymerization.
(2022) eLife. 2022 Feb 9. 11:e72483
PMID:35138249; Journal Website; PDF
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2021年
Yu-wei Pan#, Dong-ping Wu, Hua-feng Liang, Gen-yun Tang, Chun-lin Fan, Lei Shi, Wen-cai Ye, Man-mei Li*.
Hanlin Xiao#, Qinghua Zhang, Peiyun Zhong, Genyun Tang, Lijun Tao, Zhengyi Huang, Daji Guo, Yumei Liao, Yinghui Peng, Zhen-Long Wu, Ying Wang, Wen-Cai Ye,* and Lei Shi*.
Securinine Promotes Neuronal Development and Exhibits Antidepressant-like Effects via mTOR Activation.
(2021) ACS Chemical Neuroscience. 2021 Oct 6. 12(19):3650-3661.
PMID:34541857; Journal Website;
Jian-Guo Song#, Wei Tang#, Xiaojun Wang, Jun-Cheng Su, Xiao-Jun Huang, Lei Shi, Wen-Cai Ye*, Ying Wang*
Phloroglucinol-derived lipids from the leaves of Syzygium cumini and their neuroprotective activities.
(2021) Fitoterapia. 2021 Sep. 153:104968.
PMID:34147547; Journal Website;
Qi-Fang He#, Zhen-Long Wu#, Liuren Li, Wan-Yang Sun, Gui-Yang Wang, Ren-Wang Jiang, Li-Jun Hu, Lei Shi, Rong-Rong He, Ying Wang*, Wen-Cai Ye*.
Discovery of Neuritogenic Securinega Alkaloids from Flueggea suffruticosa by a Building Blocks-Based Molecular Network Strategy.
Xianman Yang#, Daji Guo#, Keshen Li, Lei Shi*.
Altered postnatal developmental patterns of ultrasonic vocalizations in Dock4 knockout mice.
(2021) Behavioural Brain Research. 2021 May 21. 406:113232.
PMID:33705839; Journal Website;
Qi-Fang He, Zhen-Long Wu, Xiao-Jun Huang, Tian-Qi Xia, Genyun Tang, Wei Tang, Lei Shi, Wen-Cai Ye*, Ying Wang*.
Cajanusoids A–D, Unusual Atropisomeric Stilbene Dimers with PTP1B Inhibitory Activities from the Leaves of Cajanus cajan.
(2021) The Journal of Organic Chemistry. 2021 Apr 16. 86(8):5870-5882.
PMID:33829799; Journal Website;
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2020年
Hui Liu#, Xiaojun Wang#, Qiaoyun Shi#, Liuren Li, Qinghua Zhang, Zhen-Long Wu, Xiao-Jun Huang, Qing-Wen Zhang, Wen-Cai Ye, Ying Wang*, Lei Shi*.
Dimeric Diarylheptanoids with Neuroprotective Activities from Rhizomes of Alpinia officinarum.
(2020) ACS Omega. 2020 Apr. 22. 5(17):10167-10175.
PMID:32391504; Journal Website;
Daji Guo#, Xiaoman Yang, Lei Shi*.
Rho GTPase Regulators and Effectors in Autism Spectrum Disorders: Animal Models and Insights for Therapeutics.
(2020) Cells. 2020 Mar 31. 9(4):835
PMID: 32244264; Journal Website;
Miaoqi Huang#, Chuanmei Liang#, Shengnan Li#, Jifeng Zhang, Daji Guo, Bo Zhao, Yuyang Liu, Yinghui Peng, Junyu Xu, Wei Liu, Guoqing Guo, Lei Shi*.
Two autism/dyslexia linked variations of DOCK4 disrupt the gene function on Rac1/Rap1 activation, neurite outgrowth, and synapse development.
(2020) Frontiers in Cellular Neuroscience. 2020 Jan 15. 13:577.
PMID:32009906; Journal website; 
PDF下载
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2019年
Jing Xu, Yong-lan Du, Jing-wei Xu, Xiao-ge Hu, Lin-fan Gu, Xiu-mao Li, Ping-hong Hu, Tai-lin Liao, Qiang-qiang Xia, Qi Sun, Lei Shi, Jianhong Luo, Jun Xia, Ziyi Wang* and Junyu Xu*.
Neuroligin 3 regulates dendritic outgrowth by modulating Akt/mTOR signaling.
(2019) Frontiers in Cellular Neuroscience. 2019 Nov 29. 13:518.
PMID:31849609; Journal website; PDF下载
Daji Guo#, Yinghui Peng#, Laijian Wang#, Xiaoyu Sun, Xiaojun Wang, Chunmei Liang, Xiaoman Yang, Shengnan Li, Junyu Xu, Wen-Cai Ye*, Bin Jiang*, Lei Shi*.
Autism-like social deficit generated by Dock4 deficiency is rescued by restoration of Rac1 and NMDA receptor function.
(2019) Molecular Psychiatry. 2021 May. 26(5):1505-1519
PMID:31388105; Journal website; PDF下载
相关报道：
【Mol Psychiatry】师蕾/蒋斌课题组揭示自闭症易感基因DOCK4调控社交行为的分子及细胞机制
Molecular Psychiatry | 暨南大学师蕾、叶文才与中山大学蒋斌在自闭症机制研究中取得新进展
Qiaoyun Shi#, Qianghua Zhang#, Yinghui Peng*, Xiaoqi Zhang, Ying Wang, Lei Shi*.
A natural diarylheptanoid protects cortical neurons against oxygen-glucose deprivation-induced autophagy and apoptosis.
(2019) Journal of Pharmacy and Pharmacology. 2019 Jul; 71(7):1110-1118. Epub 2019 Apr 25.
PMID: 31025371; Journal website; PDF下载
Xia QQ#, Xu J, Liao TL, Yu J, Shi L, Xia J, Luo JH*, Xu J*.
Neuroligins Differentially Mediate Subtype-Specific Synapse Formation in Pyramidal Neurons and Interneurons.
(2019) Neuroscience Bulletin. 2019 Jun; 35(3):497-506. Epub 2019 Feb 21.
Adorjan I#,*, Tyler T, Bhaduri A, Demharter S, Finszter CK, Bako M, Sebok OM, Nowakowski TJ, Khodosevich K, Møllgård K, Kriegstein AR, Shi L, Hoerder-Suabedissen A, Ansorge O, Molnár Z*.
Neuroserpin expression during human brain development and in adult brain revealed by immunohistochemistry and single cell RNA sequencing.
(2019) Journal of Anatomy. 2019 Sep; 235(3):543-554. Epub 2019 Jan 15.
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2018年
Zhen-Long Wu#, Xiao-Jun Huang#, Ming-Tao Xu, Xuanyue Ma, Liuren Li, Lei Shi, Wen-Jing Wang, Ren-Wang Jiang, Wen-Cai Ye*, Ying Wang*.
Flueggeacosines A-C, Dimeric Securinine-Type Alkaloid Analogues with Neuronal Differentiation Activity from Flueggea suffruticosa.
(2018) Organic Letters. 2018 Dec 7; 20(23):7703-7707. Epub 2018 Nov 28.
Xiaoyong Chen#, Yinggang Nan, Xuanyue Ma, Haiyang Liu, Wei Liu, Lei Shi*, Tuan Guo*
In-Situ Detection of Small Biomolecule Interactions using a Plasmonic Tilted Fiber Grating Sensor.
(2018) Journal of Lightwave Technology. 2019 Jun 01; 37(11):2792-2799.
Yanyang Bai#, Daji Guo, Xiaoyu Sun, Genyun Tang, Tailin Liao, Yinghui Peng, Junyu Xu, Lei Shi*
Balanced Rac1 activity controls formation and maintenance of neuromuscular acetylcholine receptor clusters.
(2018) Journal of Cell Science. 2018 Aug 10; 131(15). pii: jcs215251.
Yumei Liao#, Xiaoji Zhuang#, Xiaojie Huang, Yinghui Peng, Xuanyue Ma, Zhixing Huang, Feng Liu, Junyu Xu, Ying Wang, Wei-Min Chen*, Wen-Cai Ye*, Lei Shi*
A bivalent securinine compound SN3-L6 induces neuronal differentiation via translational upregulation of neurogenic transcription factors.
(2018) Frontiers in Pharmacology. 2018 Apr 05; 9:290.
Hui Liu#, Zhen-Long Wu#, Xiao-Jun Huang, Yinghui Peng, Xiaojie Huang, Lei Shi, Ying Wang*, Wei-Cai Ye*.
Evaluation of Diarylhepatanoid-Terpene Adduct Enantiomers from Alpinia Officinarum for Neuroprotective Activities.
(2018) Journal of Natural Products. 2018 Jan 11; 81:162-170.
PMID: 29323912；杂志网页；PDF下载
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2017年
Nan Li, Pinghong Hu, Tiantian Xu, Huan Chen, Xiaoying Chen, Jianwen Hu, Xifei Yang, Lei Shi, Jian-hong Luo, Junyu Xu.
iTRAQ-based proteomic analysis of APPSw,Ind mice provides insights into the early changes in Alzheimer's disease.
(2017) Current Alzheimer Research. 2017 Jul 19; 14(10):1109-1122.
Lancelot Jamie Millar#,*, Lei Shi, Anna Hoerder-Suabedissen, Zoltan Molnar.
Neonatal Hypoxic-Ischaemic Brain Injury: Mechanisms, Models, and Therapeutic Challenges.
(2017) Frontiers in Cellular Neuroscience. Review. 2017 May; 11:78.
Zhi-Wen Liu, Ben-qin Tang, Qing-Hua Zhang, Wen-Jing Wang, Xiao-Jun Huang, Jian Zhang, Lei Shi, Xiao-Qi Zhang*, Wen-Cai Ye*.
Ervaoffines E–G, three iboga-type alkaloids featuring ring C cleavage and rearrangement from Ervatamia officinalis.
(2017) RSC Advances. 2017 Apr; 7(35):21883-21889.
Hanlin Xiao#, Qinghua Zhang, Yinghui Peng, Genyun Tang, Yumei Liao, Xiaoji Zhuang, Wen-Cai Ye, Ying Wang, Lei Shi*.
7-(4-Hydroxy-3-methoxyphenyl)-1-phenyl-4E-hepten-3-one alleviates Abeta1-42 induced cytotoxicity through PI3K-mTOR pathways.
(2017) Biochemical and Biophysical Research Communications. 2017 Mar 4; 484(2):365-371.
Xiaoliang Xiang#, Xiaoji Zhuang, Shengnan Li, Lei Shi*.
Arhgef1 is expressed in cortical neural progenitor cells and regulates neurite outgrowth of newly differentiated neurons.
(2017) Neuroscience Letters. 2017 Jan 18; 638:27-34.
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2016年
Xiaojie Huang#, Genyun Tang#, Yumei Liao, Xiaoji Zhuang, Xiao Dong, Hui Liu, Xiao-Jun Huang, Wen-
Cai Ye, Ying Wang, Lei Shi*.
7-(4-Hydroxyphenyl)-1-phenyl-4E-hepten-3-one, a diarylheptanoid from Alpinia Officinarum, protects neurons against amyloid-β induced toxicity.
(2016) Biological & Pharmaceutical Bulletin. 2016 Dec 1; 39(12):1961-1967.
Genyun Tang#, Xin Liu#, Nan Ma#, Xiaojie Huang, Zhen-Long Wu, Wen Zhang, Ying Wang, Bing-Xin Zhao,
Zhen-Ya Wang, Fanny C. Ip, Nancy Y. Ip*, Wen-Cai Ye*, Lei Shi*, Wei-Min Chen*.
Design and Synthesis of Dimeric Securinine Analogues with Neuritogenic Activities.
(2016) ACS Chemical Neuroscience. 2016 Oct 19; 7(10):1442-1451.
Xiaoliang Xiang#, Shengnan Li, Xiaoji Zhuang, Lei Shi*.
Arhgef1 negatively regulates neurite outgrowth through activation of RhoA signaling pathways.
(2016) FEBS Letters. 2016 Sep; 590(17):2940-55.封面文章
Zhi-Wen Liu, Xiao-Jun Huang, Han-Lin Xiao, Guo Liu, Jian Zhang, Lei Shi, Ren-Wang Jiang, Xiao-Qi
Zhang*, Wen-Cai Ye*.
New iboga-type alkaloids from Ervatamia hainanensis.
(2016) RSC dvances. 6(36):30277-30284.
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2015年
Genyun Tang#, Xiao Dong#, Xiaojie Huang, Xiao-Jun Huang, Hui Liu, Ying Wang, Wen-Cai Ye*,Lei Shi*.
A natural diarylheptanoid promotes neuronal differentiation via activating ERK and PI3K-Akt dependent pathways.
(2015) Neuroscience. 303:389-401.
Yanyang Bai#, Xiaoliang Xiang, Chunmei Liang, Lei Shi*.
Regulating Rac in the nervous system: molecular function and disease implication of Rac GEFs and GAPs.
(2015) BioMed Research International. Review. 2015(2015):632450.
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2014年
Ben-Qin Tang#, Wen-Jing Wang, Xiao-Jun Huang, Guo-Qiang Li, Lei Wang*, Ren-Wang Jiang, Ting-Ting
Yang, Lei Shi, Xiao-Qi Zhang*, Wen-Cai Ye*.
Iboga-Type Alkaloids from Ervatamia officinalis.
(2014) Journal of Natural Products. 2014 Aug; 2277(8):1839-1846.
Zhen-Long Wu#, Bing-Xin Zhao#, Xiao-Jun Huang, Gen-Yun Tang, Lei Shi, Ren-Wang Jiang, Xin
Liu, Ying Wang*, Wen-Cai Ye*.
Suffrutines A and B: A Pair of Z/E Isomeric Indolizidine Alkaloids from the Roots of Flueggea suffruticosa.
(2014) Angewandte Chemie International Edition. 2014 Jun 2; 53(23):5796-5799.
Yuewen Chen#, Fanny C.F. Ip, Lei Shi, Zhe Zhang, Huibin Tang, Yu Pong Ng, Wen-Cai Ye, Amy K.Y. Fu,
Nancy Y. Ip*.
Coronin 6 regulates acetylcholine receptor clustering through modulating receptor anchorage to actin cytoskeleton.
(2014) Journal of Neuroscience. 34(7):2413–2421.
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2013年
Lei Shi*.
Dock protein family in brain development and neurological disease.
(2013) Communicative & Integrative Biology. Review. 6(6):e26839.
Yangui Xiao#,Yinghui Peng#, Jun Wan#, Genyun Tang, Yuewen Chen, Jing Tang, Wen-Cai Ye, Nancy Y. Ip,
Lei Shi*.
The atypical guanine nucleotide exchange factor Dock4 regulates neurite differentiation through modulation of Rac1 GTPase and actin dynamics.
(2013) Journal of Biological Chemistry. 288(27):20034-20045.
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2012年
Lei Shi, Amy K.Y. Fu, Nancy Y. Ip*.
Molecular mechanisms underlying the maturation and maintenance of the vertebrate neuromuscular junction.
(2012) Trends in Neurosciences. 35(7):441-53. Review.
Jacque P.K. Ip#,Lei Shi#, Yu Chen, Yasuhiro Itoh, Wing-Yu Fu, Andrea Betz, Wing-Ho Yung, Yukiko Gotoh,
Amy K.Y. Fu, Nancy Y. Ip*.
α2-chimaerin controls neuronal migration and functioning of cerebral cortex through CRMP-2.
(2012) Nature Neuroscience. 15(1): 39-47.#Equal contribution.
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2011年及以前
Zhengyu Fang#, Wantong Yao, Yi Xiong, Jiana Li, Li Liu, Lei Shi, Wei Zhang, Chao Zhang, Liping Nie, Jun
Wan*.
Attenuated expression of HRH4 in colorectal carcinomas: a potential influence on tumor growth and progression.
(2011) BMC Cancer. 11:1-11
Zhengyu Fang#, Yi Xiong, Jiana Li, Li Liu, Manhui Li, Wei Zhang, Lei Shi, Jun Wan*.
Detection of APC Gene Deletions in Colorectal Malignancies Using Quantitative PCR in a Chinese Population.
(2011) Pathology and Oncology Research. 17(3):657-661.
- PMID:21359685 ；
- 杂志网页；
- PDF下载
Lei Shi#, Amy K.Y. Fu, Nancy Y. Ip*.
Multiple roles of the Rho GEF ephexin1 in synapse remodeling.
(2010) Communicative Integrative Biological. 3(6): 622-4. Addendum.
Lei Shi#, Busma Butt, Fanny C.F. Ip, Ying Dai, Liwen Jiang, Wing-Ho Yung, Michael E. Greenberg, Amy K.Y. Fu, Nancy Y. Ip*.
Ephexin1 is required for structural maturation and neurotransmission at the neuromuscular junction.
(2010) Neuron. 65(2):204-16.
Lei Shi#, Wing-Yu Fu, Kwok-Wang Hung, Cassandra Porchetta, Christine Hall, Amy K.Y. Fu, Nancy Y. Ip*.
Alpha2-chimaerin interacts with EphA4 and regulates EphA4-dependent growth cone collapse.
(2007) Proc Natl Acad Sci U S A. 104(41):16347-52.
Wing-Yu Fu#, Yu Chen#, Mustafa Sahin, Xiao-Su Zhao, Lei Shi, Jay B Bikoff, Kwok-On Lai, Wing-Ho Yung,
Amy K.Y. Fu, Michael E Greenberg, Nancy Y. Ip*.
Cdk5 regulates EphA4-mediated dendritic spine retraction through an ephexin1-dependent mechanism.
(2007) Nature Neuroscience. 10(1):67-76.
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