Pubmed文章列表 | Google Scholar文章列表 | Researchgate文章列表
2023年
Yuxin Gao#, Yuan Guo, Yaorong Yang, Yanping Tang, Biao Wang, Qihang Yan, Xiyu Chen,Junxiang Cai, Li Fang, Ze Xiong, Fei Gao, Changjin Wu, Jizhuang Wang,* Jinyao Tang, Lei Shi*, Dan Li*.
Magnetically Manipulated Optoelectronic Hybrid Microrobots for Optically Targeted Non‐Genetic Neuromodulation.
(2023) Advanced Materials. 2023 Oct 8; e2305632.
PMID: 37805826; Journal Website
相关报道：化学与材料学院王吉壮/李丹教授团队与药学院师蕾教授团队在Adv. Mater.发表重要研究成果
暨南大学王吉壮/李丹教授团队与师蕾教授团队Adv. Mater.：硅基复合微机器人用于精准光神经调节
Xiao-Ling Zhan#, Ning Pan#, Shamshad Karatela, Lei Shi, Xin Wang, Zhao-Yan Liu, Jin Jing, Xiu-Hong Li, Li Cai, Li-Zi Lin*.
Infant feeding practices and autism spectrum disorder in US children aged 2-5 years: the national survey of children's health (NSCH) 2016-2020.
(2023) International Breastfeeding Journal. 2023 Aug 11;18(1):41.
PMID: 37568201; Journal Website
Ning Pan#, Li-Zi Lin, Xin Wang,Lei Shi, Xiao-Yu Xu, Yu-Ying Jin, Si Tan, Xiao-Jing Song, Jin Jing, Xiu-Hong Li*.
Brain structure underlying the empathizing-systemizing difference in children with autism spectrum disorder.
(2023) World Journal of Pediatrics. 2023 Aug;19(8):782-792.
PMID: 37273174; Journal Website
Zhi-Wen Liu, Min Song, Jun-Ya Wang, De-Zhi Wang, Biao Sun, Lei Shi, Ren-Wang Jiang, Min Ma, Xiao-Qi Zhang.
Monoterpenoid indole alkaloid adducts and dimers from Melodinus fusiformis.
(2023) Phytochemistry. 2023 Jul; 211:113678.
PMID: 37059289; Journal Website
Liao, Yumei#, Jun-Ya Wang, Yan Pan, Xueyi Zou, Chaoqun Wang, Yinghui Peng, Yun-Lin Ao, Mei Fong Lam, Xiaoshen Zhang, Xiao-Qi Zhang*, Lei Shi, Shiqing Zhang*.
The Protective Effect of (-)-Tetrahydroalstonine against OGD/R-Induced Neuronal Injury via Autophagy Regulation.
(2023) Molecules. 2023 Mar 4; 28(5):2370.
PMID: 36903613; Journal Website
Yinghui Peng#, Miaoqi Huang#, Jiaoyan Xie, Beiyi Shu, Xiaojun Wang, Yumei Liao, Junyu Xu, Lei Shi*.
Translational patterns of ionotropic glutamate and GABA receptors during brain development and behavioral stimuli revealed by polysome profiling.
(2023)Journal of Neurochemistry. 2023 Mar; 164(6):786-812.
PMID: 36695027; Journal Website
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2022年
Lijiao Zu#, Jiwei Xie, Peng Liu, Xuejun Zhang, Weiru Liu, Zhencheng Li, Shiqing Zhang, Lihong Zhu, Lei Shi, Tuan Guo, Kaiwei Li, Wei Bi, Francesco Chiavaioli*.
Ultra-sensitive Detection of Alzheimer’s Biosmarkers Using Plasmonic Optical Fiber Sensors.
(2022) Asia Communications and Photonics Conference, Shenzhen, China, 2022, pp. 2025-2028, doi: 10.1109/ACP55869.2022.10088486.
Cunzheng Li, Ji-An Wei, Diyang Wang, Zhihua Luo, Chaoqin Pang, Kai Chen, Juan Duan, Bailing Chen, Libing Zhou, Fadel Tissir, Lei Shi, Kwok-Fai So, Li Zhang*, Yibo Qu*.
Planar cell polarity protein Celsr2 maintains structural and functional integrity of adult cortical synapses.
(2022) Progress In Neurobiology. 2022 Dec. 219:102352
PMID: 36089108; Journal Website
Xuanyue Ma#, Liuren Li#, Ziming Li#, Zhengyi Huang, Yaorong Yang, Peng Liu, Daji Guo, Yueyao Li, Tianying Wu, Ruixiang Luo, Junyu Xu, Wen-Cai Ye*, Bin Jiang*, Lei Shi*.
eEF2 in the prefrontal cortex promotes excitatory synaptic transmission and social novelty behavior.
(2022) EMBO Reports. 2022 Aug 22. e54543
PMID: 35993189; Journal Website; PDF
Francesco Chiavaioli*, Desiree Santano Rivero, Ignacio Del Villar*, Abián B Socorro‐Leránoz, Xuejun Zhang, Kaiwei Li, Enrique Santamaría, Joaquín Fernández-Irigoyen, Francesco Baldini, Daniel LA van den Hove, Lei Shi, Wei Bi, Tuan Guo*, Ambra Giannetti, Ignacio R Matias.
Ultrahigh Sensitive Detection of Tau Protein as Alzheimer's Biomarker via Microfluidics and Nanofunctionalized Optical Fiber Sensors.
(2022) Advanced Photonics Research. 2022 July 18. DOI:10.1002/adpr.202200044
PMID; Journal Website; PDF
Daji Guo#,*, Xiaoman Yang#, Ming Gao#, Xiaoqing Chen, Yanping Tang, Lingling Shen, Keshen Li*, Lei Shi*.
Deficiency of autism-reulated gene Dock4 leads to impaired spatial memory and hippocampal function in mice at late middle age.
(2022) Cellular and Molecular Neurobiology. 2022 May 30. DOI:10.1007/s10571-022-01233-4
PMID: 35635601; Journal Website; PDF
Yanling Huang#, Yaorong Yang#, Yawen Zhao, Daji Guo, Linxi Chen, Lei Shi*, Geyang Xu*.
DOCK4 regulates ghrelin production in gastric X/A-like cells.
(2022) Journal of Endocrinological Investigation. 2022 Jul.45(7):1447-1454
PMID: 35302184; Journal Website; PDF
Rui Zheng#, Yonglan Du#, Xintai Wang, Tailin Liao, Zhe Zhang, Na Wang, Xiumao Li, Ying Shen, Lei Shi, Jianhong Luo*, Jun Xia*, Ziyi Wang*, Junyu Xu*.
KIF2C regulates synaptic plasticity and cognition in mice through dynamic microtubule depolymerization.
(2022) eLife. 2022 Feb 9. 11:e72483
PMID:35138249; Journal Website; PDF
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2021年
Yu-wei Pan#, Dong-ping Wu, Hua-feng Liang, Gen-yun Tang, Chun-lin Fan, Lei Shi, Wen-cai Ye, Man-mei Li*.
Hanlin Xiao#, Qinghua Zhang, Peiyun Zhong, Genyun Tang, Lijun Tao, Zhengyi Huang, Daji Guo, Yumei Liao, Yinghui Peng, Zhen-Long Wu, Ying Wang, Wen-Cai Ye,* and Lei Shi*.
Securinine Promotes Neuronal Development and Exhibits Antidepressant-like Effects via mTOR Activation.
(2021) ACS Chemical Neuroscience. 2021 Oct 6. 12(19):3650-3661.
PMID:34541857; Journal Website; 
PDF
Jian-Guo Song#, Wei Tang#, Xiaojun Wang, Jun-Cheng Su, Xiao-Jun Huang, Lei Shi, Wen-Cai Ye*, Ying Wang*
Phloroglucinol-derived lipids from the leaves of Syzygium cumini and their neuroprotective activities.
(2021) Fitoterapia. 2021 Sep. 153:104968.
PMID:34147547; Journal Website; PDF
Qi-Fang He#, Zhen-Long Wu#, Liuren Li, Wan-Yang Sun, Gui-Yang Wang, Ren-Wang Jiang, Li-Jun Hu, Lei Shi, Rong-Rong He, Ying Wang*, Wen-Cai Ye*.
Discovery of Neuritogenic Securinega Alkaloids from Flueggea suffruticosa by a Building Blocks-Based Molecular Network Strategy.
Xianman Yang#, Daji Guo#, Keshen Li, Lei Shi*.
Altered postnatal developmental patterns of ultrasonic vocalizations in Dock4 knockout mice.
(2021) Behavioural Brain Research. 2021 May 21. 406:113232.
PMID:33705839; Journal Website; PDF
Qi-Fang He, Zhen-Long Wu, Xiao-Jun Huang, Tian-Qi Xia, Genyun Tang, Wei Tang, Lei Shi, Wen-Cai Ye*, Ying Wang*.
Cajanusoids A–D, Unusual Atropisomeric Stilbene Dimers with PTP1B Inhibitory Activities from the Leaves of Cajanus cajan.
(2021) The Journal of Organic Chemistry. 2021 Apr 16. 86(8):5870-5882.
PMID:33829799; Journal Website; PDF
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2020年
Hui Liu#, Xiaojun Wang#, Qiaoyun Shi#, Liuren Li, Qinghua Zhang, Zhen-Long Wu, Xiao-Jun Huang, Qing-Wen Zhang, Wen-Cai Ye, Ying Wang*, Lei Shi*.
Dimeric Diarylheptanoids with Neuroprotective Activities from Rhizomes of Alpinia officinarum.
(2020) ACS Omega. 2020 Apr. 22. 5(17):10167-10175.
PMID:32391504; Journal Website; PDF
Daji Guo#, Xiaoman Yang, Lei Shi*.
Rho GTPase Regulators and Effectors in Autism Spectrum Disorders: Animal Models and Insights for Therapeutics.
(2020) Cells. 2020 Mar 31. 9(4):835
PMID: 32244264; Journal Website; PDF
Miaoqi Huang#, Chuanmei Liang#, Shengnan Li#, Jifeng Zhang, Daji Guo, Bo Zhao, Yuyang Liu, Yinghui Peng, Junyu Xu, Wei Liu, Guoqing Guo, Lei Shi*.
Two autism/dyslexia linked variations of DOCK4 disrupt the gene function on Rac1/Rap1 activation, neurite outgrowth, and synapse development.
(2020) Frontiers in Cellular Neuroscience. 2020 Jan 15. 13:577.
PMID:32009906; Journal website; PDF下载
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2019年
Jing Xu, Yong-lan Du, Jing-wei Xu, Xiao-ge Hu, Lin-fan Gu, Xiu-mao Li, Ping-hong Hu, Tai-lin Liao, Qiang-qiang Xia, Qi Sun, Lei Shi, Jianhong Luo, Jun Xia, Ziyi Wang* and Junyu Xu*.
Neuroligin 3 regulates dendritic outgrowth by modulating Akt/mTOR signaling.
(2019) Frontiers in Cellular Neuroscience. 2019 Nov 29. 13:518.
PMID:31849609; Journal website; PDF下载
Daji Guo#, Yinghui Peng#, Laijian Wang#, Xiaoyu Sun, Xiaojun Wang, Chunmei Liang, Xiaoman Yang, Shengnan Li, Junyu Xu, Wen-Cai Ye*, Bin Jiang*, Lei Shi*.
Autism-like social deficit generated by Dock4 deficiency is rescued by restoration of Rac1 and NMDA receptor function.
(2019) Molecular Psychiatry. 2021 May. 26(5):1505-1519
PMID:31388105; Journal website; PDF下载
相关报道：
【Mol Psychiatry】师蕾/蒋斌课题组揭示自闭症易感基因DOCK4调控社交行为的分子及细胞机制
Molecular Psychiatry | 暨南大学师蕾、叶文才与中山大学蒋斌在自闭症机制研究中取得新进展
Qiaoyun Shi#, Qianghua Zhang#, Yinghui Peng*, Xiaoqi Zhang, Ying Wang, Lei Shi*.
A natural diarylheptanoid protects cortical neurons against oxygen-glucose deprivation-induced autophagy and apoptosis.
(2019) Journal of Pharmacy and Pharmacology. 2019 Jul; 71(7):1110-1118. Epub 2019 Apr 25.
PMID: 31025371; Journal website; PDF下载
Xia QQ#, Xu J, Liao TL, Yu J, Shi L, Xia J, Luo JH*, Xu J*.
Neuroligins Differentially Mediate Subtype-Specific Synapse Formation in Pyramidal Neurons and Interneurons.
(2019) Neuroscience Bulletin. 2019 Jun; 35(3):497-506. Epub 2019 Feb 21.
Adorjan I#,*, Tyler T, Bhaduri A, Demharter S, Finszter CK, Bako M, Sebok OM, Nowakowski TJ, Khodosevich K, Møllgård K, Kriegstein AR, Shi L, Hoerder-Suabedissen A, Ansorge O, Molnár Z*.
Neuroserpin expression during human brain development and in adult brain revealed by immunohistochemistry and single cell RNA sequencing.
(2019) Journal of Anatomy. 2019 Sep; 235(3):543-554. Epub 2019 Jan 15.
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2018年
Zhen-Long Wu#, Xiao-Jun Huang#, Ming-Tao Xu, Xuanyue Ma, Liuren Li, Lei Shi, Wen-Jing Wang, Ren-Wang Jiang, Wen-Cai Ye*, Ying Wang*.
Flueggeacosines A-C, Dimeric Securinine-Type Alkaloid Analogues with Neuronal Differentiation Activity from Flueggea suffruticosa.
(2018) Organic Letters. 2018 Dec 7; 20(23):7703-7707. Epub 2018 Nov 28.
Xiaoyong Chen#, Yinggang Nan, Xuanyue Ma, Haiyang Liu, Wei Liu, Lei Shi*, Tuan Guo*
In-Situ Detection of Small Biomolecule Interactions using a Plasmonic Tilted Fiber Grating Sensor.
(2018) Journal of Lightwave Technology. 2019 Jun 01; 37(11):2792-2799.
Yanyang Bai#, Daji Guo, Xiaoyu Sun, Genyun Tang, Tailin Liao, Yinghui Peng, Junyu Xu, Lei Shi*
Balanced Rac1 activity controls formation and maintenance of neuromuscular acetylcholine receptor clusters.
(2018) Journal of Cell Science. 2018 Aug 10; 131(15). pii: jcs215251.
Yumei Liao#, Xiaoji Zhuang#, Xiaojie Huang, Yinghui Peng, Xuanyue Ma, Zhixing Huang, Feng Liu, Junyu Xu, Ying Wang, Wei-Min Chen*, Wen-Cai Ye*, Lei Shi*
A bivalent securinine compound SN3-L6 induces neuronal differentiation via translational upregulation of neurogenic transcription factors.
(2018) Frontiers in Pharmacology. 2018 Apr 05; 9:290.
Hui Liu#, Zhen-Long Wu#, Xiao-Jun Huang, Yinghui Peng, Xiaojie Huang, Lei Shi, Ying Wang*, Wei-Cai Ye*.
Evaluation of Diarylhepatanoid-Terpene Adduct Enantiomers from Alpinia Officinarum for Neuroprotective Activities.
(2018) Journal of Natural Products. 2018 Jan 11; 81:162-170.
PMID: 29323912；杂志网页；PDF下载
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2017年
Nan Li, Pinghong Hu, Tiantian Xu, Huan Chen, Xiaoying Chen, Jianwen Hu, Xifei Yang, Lei Shi, Jian-hong Luo, Junyu Xu.
iTRAQ-based proteomic analysis of APPSw,Ind mice provides insights into the early changes in Alzheimer's disease.
(2017) Current Alzheimer Research. 2017 Jul 19; 14(10):1109-1122.
Lancelot Jamie Millar#,*, Lei Shi, Anna Hoerder-Suabedissen, Zoltan Molnar.
Neonatal Hypoxic-Ischaemic Brain Injury: Mechanisms, Models, and Therapeutic Challenges.
(2017) Frontiers in Cellular Neuroscience. Review. 2017 May; 11:78.
Zhi-Wen Liu, Ben-qin Tang, Qing-Hua Zhang, Wen-Jing Wang, Xiao-Jun Huang, Jian Zhang, Lei Shi, Xiao-Qi Zhang*, Wen-Cai Ye*.
Ervaoffines E–G, three iboga-type alkaloids featuring ring C cleavage and rearrangement from Ervatamia officinalis.
(2017) RSC Advances. 2017 Apr; 7(35):21883-21889.
Hanlin Xiao#, Qinghua Zhang, Yinghui Peng, Genyun Tang, Yumei Liao, Xiaoji Zhuang, Wen-Cai Ye, Ying Wang, Lei Shi*.
7-(4-Hydroxy-3-methoxyphenyl)-1-phenyl-4E-hepten-3-one alleviates Abeta1-42 induced cytotoxicity through PI3K-mTOR pathways.
(2017) Biochemical and Biophysical Research Communications. 2017 Mar 4; 484(2):365-371.
Xiaoliang Xiang#, Xiaoji Zhuang, Shengnan Li, Lei Shi*.
Arhgef1 is expressed in cortical neural progenitor cells and regulates neurite outgrowth of newly differentiated neurons.
(2017) Neuroscience Letters. 2017 Jan 18; 638:27-34.
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2016年
Xiaojie Huang#, Genyun Tang#, Yumei Liao, Xiaoji Zhuang, Xiao Dong, Hui Liu, Xiao-Jun Huang, Wen-
Cai Ye, Ying Wang, Lei Shi*.
7-(4-Hydroxyphenyl)-1-phenyl-4E-hepten-3-one, a diarylheptanoid from Alpinia Officinarum, protects neurons against amyloid-β induced toxicity.
(2016) Biological & Pharmaceutical Bulletin. 2016 Dec 1; 39(12):1961-1967.
Genyun Tang#, Xin Liu#, Nan Ma#, Xiaojie Huang, Zhen-Long Wu, Wen Zhang, Ying Wang, Bing-Xin Zhao,
Zhen-Ya Wang, Fanny C. Ip, Nancy Y. Ip*, Wen-Cai Ye*, Lei Shi*, Wei-Min Chen*.
Design and Synthesis of Dimeric Securinine Analogues with Neuritogenic Activities.
(2016) ACS Chemical Neuroscience. 2016 Oct 19; 7(10):1442-1451.
Xiaoliang Xiang#, Shengnan Li, Xiaoji Zhuang, Lei Shi*.
Arhgef1 negatively regulates neurite outgrowth through activation of RhoA signaling pathways.
(2016) FEBS Letters. 2016 Sep; 590(17):2940-55.封面文章
Zhi-Wen Liu, Xiao-Jun Huang, Han-Lin Xiao, Guo Liu, Jian Zhang, Lei Shi, Ren-Wang Jiang, Xiao-Qi
Zhang*, Wen-Cai Ye*.
New iboga-type alkaloids from Ervatamia hainanensis.
(2016) RSC dvances. 6(36):30277-30284.
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2015年
Genyun Tang#, Xiao Dong#, Xiaojie Huang, Xiao-Jun Huang, Hui Liu, Ying Wang, Wen-Cai Ye*,Lei Shi*.
A natural diarylheptanoid promotes neuronal differentiation via activating ERK and PI3K-Akt dependent pathways.
(2015) Neuroscience. 303:389-401.
Yanyang Bai#, Xiaoliang Xiang, Chunmei Liang, Lei Shi*.
Regulating Rac in the nervous system: molecular function and disease implication of Rac GEFs and GAPs.
(2015) BioMed Research International. Review. 2015(2015):632450.
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2014年
Ben-Qin Tang#, Wen-Jing Wang, Xiao-Jun Huang, Guo-Qiang Li, Lei Wang*, Ren-Wang Jiang, Ting-Ting
Yang, Lei Shi, Xiao-Qi Zhang*, Wen-Cai Ye*.
Iboga-Type Alkaloids from Ervatamia officinalis.
(2014) Journal of Natural Products. 2014 Aug; 2277(8):1839-1846.
Zhen-Long Wu#, Bing-Xin Zhao#, Xiao-Jun Huang, Gen-Yun Tang, Lei Shi, Ren-Wang Jiang, Xin
Liu, Ying Wang*, Wen-Cai Ye*.
Suffrutines A and B: A Pair of Z/E Isomeric Indolizidine Alkaloids from the Roots of Flueggea suffruticosa.
(2014) Angewandte Chemie International Edition. 2014 Jun 2; 53(23):5796-5799.
Yuewen Chen#, Fanny C.F. Ip, Lei Shi, Zhe Zhang, Huibin Tang, Yu Pong Ng, Wen-Cai Ye, Amy K.Y. Fu,
Nancy Y. Ip*.
Coronin 6 regulates acetylcholine receptor clustering through modulating receptor anchorage to actin cytoskeleton.
(2014) Journal of Neuroscience. 34(7):2413–2421.
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2013年
Lei Shi*.
Dock protein family in brain development and neurological disease.
(2013) Communicative & Integrative Biology. Review. 6(6):e26839.
Yangui Xiao#,Yinghui Peng#, Jun Wan#, Genyun Tang, Yuewen Chen, Jing Tang, Wen-Cai Ye, Nancy Y. Ip,
Lei Shi*.
The atypical guanine nucleotide exchange factor Dock4 regulates neurite differentiation through modulation of Rac1 GTPase and actin dynamics.
(2013) Journal of Biological Chemistry. 288(27):20034-20045.
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2012年
Lei Shi, Amy K.Y. Fu, Nancy Y. Ip*.
Molecular mechanisms underlying the maturation and maintenance of the vertebrate neuromuscular junction.
(2012) Trends in Neurosciences. 35(7):441-53. Review.
Jacque P.K. Ip#,Lei Shi#, Yu Chen, Yasuhiro Itoh, Wing-Yu Fu, Andrea Betz, Wing-Ho Yung, Yukiko Gotoh,
Amy K.Y. Fu, Nancy Y. Ip*.
α2-chimaerin controls neuronal migration and functioning of cerebral cortex through CRMP-2.
(2012) Nature Neuroscience. 15(1): 39-47.#Equal contribution.
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2011年及以前
Zhengyu Fang#, Wantong Yao, Yi Xiong, Jiana Li, Li Liu, Lei Shi, Wei Zhang, Chao Zhang, Liping Nie, Jun
Wan*.
Attenuated expression of HRH4 in colorectal carcinomas: a potential influence on tumor growth and progression.
(2011) BMC Cancer. 11:1-11
Zhengyu Fang#, Yi Xiong, Jiana Li, Li Liu, Manhui Li, Wei Zhang, Lei Shi, Jun Wan*.
Detection of APC Gene Deletions in Colorectal Malignancies Using Quantitative PCR in a Chinese Population.
(2011) Pathology and Oncology Research. 17(3):657-661.
- PMID:21359685 ；
- 杂志网页；
- PDF下载
Lei Shi#, Amy K.Y. Fu, Nancy Y. Ip*.
Multiple roles of the Rho GEF ephexin1 in synapse remodeling.
(2010) Communicative Integrative Biological. 3(6): 622-4. Addendum.
Lei Shi#, Busma Butt, Fanny C.F. Ip, Ying Dai, Liwen Jiang, Wing-Ho Yung, Michael E. Greenberg, Amy K.Y. Fu, Nancy Y. Ip*.
Ephexin1 is required for structural maturation and neurotransmission at the neuromuscular junction.
(2010) Neuron. 65(2):204-16.
Lei Shi#, Wing-Yu Fu, Kwok-Wang Hung, Cassandra Porchetta, Christine Hall, Amy K.Y. Fu, Nancy Y. Ip*.
Alpha2-chimaerin interacts with EphA4 and regulates EphA4-dependent growth cone collapse.
(2007) Proc Natl Acad Sci U S A. 104(41):16347-52.
Wing-Yu Fu#, Yu Chen#, Mustafa Sahin, Xiao-Su Zhao, Lei Shi, Jay B Bikoff, Kwok-On Lai, Wing-Ho Yung,
Amy K.Y. Fu, Michael E Greenberg, Nancy Y. Ip*.
Cdk5 regulates EphA4-mediated dendritic spine retraction through an ephexin1-dependent mechanism.
(2007) Nature Neuroscience. 10(1):67-76.
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